Reading assignment:
If you're feeling ambitious you may want to read the MUSCLE papers (and this one) as well as the ProbCons paper.
I'll go over them in quite a bit of detail on Tuesday, as both describe innovative and interesting MSA algorithms.
Also, chapter 6 in the Durbin book gives an excellent overview of multiple sequence alignment. The multiple sequence alignment chapter in Mount is very useful as well.
Also, I gave a lecture to Jonathan Pevsner's bioinformatics class on MSA and you may find that to be a useful resource, as it covers many available MSA programs and databases that we don't have time to cover here.
If you're feeling ambitious you may want to read the MUSCLE papers (and this one) as well as the ProbCons paper.
I'll go over them in quite a bit of detail on Tuesday, as both describe innovative and interesting MSA algorithms.
Also, chapter 6 in the Durbin book gives an excellent overview of multiple sequence alignment. The multiple sequence alignment chapter in Mount is very useful as well.
Also, I gave a lecture to Jonathan Pevsner's bioinformatics class on MSA and you may find that to be a useful resource, as it covers many available MSA programs and databases that we don't have time to cover here.