Biostatistics 140.651 and 140.652 Methods in Biostatistics I and II

Calendar

All dates for the lecture notes are tentative. Except for the final homework of 140.652, homeworks are due Friday before 5:00 PM in the Biostatistics main office E3527. The final homework of 652 is due 12/18 at 5:00 PM in the Biostat main office. Note, students are responsible for corrections and additional examples covered in class. Some of the later links are dead as the content is being revised.

651

Date Subject Reading Comments
8/30 Set theory basics, probability Lecture 1 Chapter 1
9/4 Introduction to probability Lecture 2 3.1-3.5, 4.1-4.3, 5.1-5.2
9/6 Expected values Lecture 3 4.4-4.5, 4.9 HW 1 is due 9/7
9/11 Random vectors, independence Lecture 4 3.4
9/13 Conditional probabilities, Bayes rule Lecture 5 3.6-3.9
9/18 Likelihood Lecture 6
9/20 Distributions Lecture 7 4.8, 4.9, 5.1-5.6 HW 2 is due 9/21
9/25 Midterm exam
9/27 Asymptotics Lecture 86.1,6.2,6.5
10/2 Confidence intervals Lecture 9 6.7,6.8
10/4 Confidence intervals Lecture 10 8.3, 8.5 HW 3 is due 10/5
10/9Some basic plots lecture11 and Karl's slides on bad plotting Chapter 2
10/11Bootstrapping lecture 12 and Tom's notes
10/16Confidence intervals for binomial proportions lecture 13 and confidence interval interpretations 6.8
10/18Logs, geometric meansLecture 14 and Exam review HW 4 is due 10/19
10/23 Final exam


652

Date Subject Reading Comments
10/25Hypothesis Testing Lecture 15 also see these files7.1-7.7
10/30Power and sample size and two group tests Lecture 16 and Lecture 17; also look at these review notes about hypothesis testing 8.1-8.8 8.10-8.12
11/1 Tests for binomial proportions Lecture 187.10 HW 5 due 11/2
11/6 Two sample binomial tests, delta method Lecture 19 and Lecture 20 10.1, 10.2, 13.1-13.3
11/8 Fisher's exact tests, Chi-squared tests Lecture 21 Lecture 22 also, some notes on the multinomial distribution 10.2,10.3-10.6-10.9
11/13 Simpson's pardox, confounding Lecture 23 13.4,13.5
11/15 Retrospective case-control studies, exact inference for the odds ratio Lecture 2413.1-13.3 HW 6 due 11/16; also task1.csv
11/22 No class
11/27 Methods for matched pairs, McNemar's, conditional versus marginal odds ratiosLecture 25 10.4
11/29 Midterm Exam
12/4 Non-parametric tests, permutation tests Lecture 26 Chapter 9
12/6 Inference for Poisson counts Lecture 27 14.1-14.3 HW 7 due 12/7
12/11 Multiplicity Lecture 28 pages 573-576, 579-581
12/13 ROC curves Lecture 29
12/18 More contingency table stuff Lecture 30 10.8HW 8 due 12/18
12/20 Final Exam some quotes