Brian L. Egleston, Ph.D.

    Alumnus, Department of Biostatistics

    Johns Hopkins University

   

    Current position:

    Assistant Member

    Biostatistics Facility

    Fox Chase Cancer Center

    Philadelphia, PA

    e-mail: Brian.Egleston@fccc.edu

   

   


AdvisorDr. Daniel Scharfstein

     Associate Professor

     Department of Biostatistics

     Johns Hopkins University


 

Research Interests

Causal inference

Competing risks

Statistical tools for investigating mediation

Translational research

Nonparametric and semiparametric estimation

 

Broadly, I am interested in developing statistical methodologies applicable to health services research. I started my career in public policy and health services research. This led to an interest in causal modeling of treatment and exposure effects. Causal modeling requires close collaboration between scientists and statisticians; given scientifically-valid assumptions and causal pathways, statistics can be used to quantify causal effects. My current work on causal models uses Rubin's potential outcomes framework in which we conceptualize the potential outcomes that participants would have under both exposure arms of a study. I have worked on causal methods for investigations of exposure effects on non-mortality outcomes when death is a competing risk and investigations of mediation.

Education

B.A. in Political Science, 1992, Tufts University, Medford, MA

Master of Public Policy with Honors, 1997, University of Chicago, IL

Ph.D. in Biostatistics, Johns Hopkins School of Public Health, 2006

 

Papers Completed During or Before My Years at Hopkins

MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, Salkever DS, Scharfstein DO.  A national evaluation of the effect of trauma-center care on mortality.  New England Journal of Medicine 2006; 354:366-378. in press.

 

Freeman EE, Egleston BL, West SK, Bandeen-Roche K, Rubin G.  Visual Acuity Change and Mortality in Older Adults. Investigative Opthamology and Visual Science 2005; 46(11):4040-5.

Merenstein D, Egleston BL, Diener-West M.  Are Longer Lengths of Stay and Increased Costs Associated with Children's Hospitals? Pediatrics 2005; 115(4):839-844.

Egleston BL , Scharfstein DO, Freeman EE, West SK. "Causal Inference for Non-mortality Outcomes in the Presence of Death" (December 14, 2004). Johns Hopkins University, Dept. of Biostatistics Working Papers. Working Paper 69.   Also under revision at Biostatistics. (Click for link to this paper)

 

Meltzer D, Egleston B , Abdalla I.  Patterns of prostate cancer treatment by clinical stage and age. Am J Public Health. 2001; 91(1):126-8.

 

Meltzer D, Egleston B , Stoffel D, Dasbach E. Effect of future costs on cost-effectiveness of medical interventions among young adults: the example of intensive therapy for type 1 diabetes mellitus.  Med Care. 2000; 38(6):679-85.

 

Egleston BL , Rudberg MA, Brody JA.   State variation in nursing home mortality outcomes according to do-not-resuscitate status.  J Gerontol A Biol Sci Med Sci. 2000; 55(4):M215-20.

 

Egleston BL , Rudberg MA, Brody JA. Prior Living Arrangements and Nursing Home Resident Admission ADL Characteristics: A Study of Two States.  J Gerontol B Psychol Sci Soc Sci 1999; 54: S202-S206.

 

Meltzer D, Egleston B.   How patients with diabetes perceive their risk for major complications.  Eff Clin Pract. 2000; 3(1):7-15.

 

Rudberg MA, Egleston BL, Grant MD, Brody JA. Effectiveness of feeding tubes in nursing home residents with swallowing disorders. JPEN J Parenter Enteral Nutr. 2000; 24(2):97-102.

 

Suri DN, Egleston BL, Brody JA, Rudberg MA.   Nursing home resident use of care directives.  J Gerontol A Biol Sci Med Sci. 1999; 54(5):M225-9.

 

Heymann SJ, Earle A, Egleston B . Parental availability for the care of sick children.   Pediatrics 1996. 98(2 Pt 1):226-30.