Wei-Min Chen's Home Page 

Education:

1992-1996 BS, statistics, Department of Probability & Statistics, Peking University

1996-1998 MS program, computer vision and image processing, Center for Information Sciences, Peking University. Advisor: Qing-Yun Shi

1998-2000 MS, statistical genetics, Department of Biomedical Sciences & Osteoporosis Research Center, Creighton University. Advisor: Hong-Wen Deng

2000-2004 PhD, biostatistics, Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health. Advisors: Karl Broman and Kung-Yee Liang

2004-?       Postdoctoral Fellow, Center for Statistical Genetics, University of Michigan School of Public Health. Advisor: Goncalo Abecasis

Software: 

I wrote and maintain the following computer programs:

  LinkageExplorer (2003-2004)

     LinkageExplorer can help a statistical geneticist to investigate problems in linkage analysis

  GeneFinder (2002-2004) published in Genetic Analysis Software on Rockefeller website

    GeneFinder is a computer program developed by Dr. Kung-Yee Liang's group, to localize disease susceptibility genes using GEE approach and pedigree data

  TDT Power Calculator  (2001) published in Genetic Analysis Software on Rockefeller website

    TDT-PC can help gene-mappers to calculate the statistical power of the Transmission/Disequilibrium test in association study

Selected Publications:

Chen WM, Broman KW, Liang KY (2005) Power and robustness of linkage tests for quantitative traits in general pedigrees. Genet Epidemiol 28:11-23 [161kb, in PDF format][associated computer program]

Chen WM, Broman KW, Liang KY (2004) Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression. Genet Epidemiol May;26(4):265-272 [Abstract in PubMed] [131KB, in PDF format] [associated computer program]

Chen WM, Deng HW (2001) A general and accurate approach for computing the statistical power of the transmission disequilibrium test for complex disease genes. Genet Epidemiol Jul;21:53-67 [Abstract in PubMed] [98kb, in PDF format] [associated computer program]

......

Research Interests:

My main area of interest is the implementation of mathematical and statistical methods in human genetics. 

Email: wechen@umich.edu        

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