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Dr. Diener-West's research interests have
focused on the design, conduct, and analysis of clinical trials.
For 20 years, she was the Study Statistician and Deputy Director
of the Coordinating Center for the Collaborative Ocular Melanoma
Study (COMS). The COMS is a set of long-term multicenter clinical
trials sponsored by the National Eye Institute and conducted at
43 clinical centers to investigate the effectiveness of different
radiation treatments on prolonging survival of patients with choroidal
melanoma. Areas of interest have included risk factors for mortality
and predictors of growth of small melanoma, agreement among multiple
raters, and correlation of different methods of measuring tumor
dimensions. Other research interests include treatment trials
for cystic fibrosis and a longitudinal assessment of the relationship
between sleep disorders and heart disease in the Sleep Heart Health
Study. She is a member of the faculty of the Johns Hopkins Center
for Clinical Trials.
Dr. Diener-West's interests also focus
on the statistical education of health professionals. Since 1990,
she has taught courses in introductory statistical methods and
data analysis. With Dr. Sukon Kancharaksa, she developed and co-instructs
in the course Fundamentals of Epidemiology, the School's first
distance education course.