DEPARTMENT OF BIOSTATISTICS
Johns Hopkins School
of Public Health

 

Causal Inference (Biostatistics 140.665)

Instructor Constantine E. Frangakis

Meeting time Tuesdays, Thursdays 15:00-16:20 pm, W4007

Email: cfrangak@jhsph.edu,

About this course:   

An important task in public health and medicine is to evaluate and compare treatments, programs, and therapies.  To make accurate evaluations, it is important to study (and respect) data on people, that is, which treatments  we take and what outcomes we eventually have. For practical and ethical reasons, studies with people go beyond the experimental control found in fully laboratory settings, so people who take one treatment can generally be different prognostically from those who take another treatment. Causal inference means the framework for defining what we care about, for designing and analyzing studies, to take data we can observe between different treatment groups and correctly attribute them to effects of treatments.  The course presents recent developments in designs and methods to better evaluate treatment effects.
 

The instructor acknowledges the sharing of ideas and material with Donald Rubin and Guido Imbens

Syllabus

Summaries of the lectures will be posted after each class

Lecture notes

  Chapter 1. Introduction and framework

  Chapter 2. Completely randomized assignment

  Chapter 3. Treatment assignment with known and varying probabilities

  Chapter 4. Ignorable treatment assignment and propensity scores   Supplement on likelihood

  Chapter 5. Studies with multiple treatments -- sequential ignorable assignment

  Chapter 6. Studies with nonignorable noncompliance: instrumental variables

  Chapter 7. Studies with multiple partially controlled factors

Problem sets

  Problem Set 1   Outline to solution to PS1

  Problem Set 2   Data