Constantine Frangakis
Department of Biostatistics
Bloomberg School of Public Health
Johns Hopkins University
cfrangak@jhsph.edu

Causal Inference
(Biostatistics 140.665)

Meeting times: Tuesdays, Thursdays 3:00-4:20 pm, W4007
Instructor: Constantine E. Frangakis, Associate Professor, Biostatistics, Hygiene E3642
   cfrangak@jhsph.edu

Course description

An important task in public health and medicine is to evaluate and compare treatments, programs, and therapies.  To make accurate evaluations, it is important to study (and respect) data on people, that is, which treatments  we take and what outcomes we eventually have. For practical and ethical reasons, studies with people go beyond the experimental control found in fully laboratory settings, so people who take one treatment can generally be different prognostically from those who take another treatment. Causal inference means the framework for defining what we care about, for designing and analyzing studies, to take data we can observe between different treatment groups and correctly attribute them to effects of treatments.  The course presents recent developments in designs and methods to better evaluate treatment effects.

The instructor acknowledges the sharing of ideas and material with Donald Rubin and Guido Imbens

Syllabus

Summaries of the lectures will be posted after each class

Lecture notes

Chapter 1. Introduction and framework

Chapter 2. Completely randomized assignment

Chapter 3. Treatment assignment with known and varying probabilities

Chapter 4. Ignorable treatment assignment and propensity scores   Supplement on likelihood

Chapter 5. Studies with multiple treatments -- sequential ignorable assignment

Chapter 6. Studies with nonignorable noncompliance: instrumental variables

Chapter 7. Studies with multiple partially controlled factors


Problem sets

Problem Set 1  

Problem Set 2   Data

Problem Set 4


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